MOOSE is the Multiscale Object-Oriented Simulation Environment. It is the base and numerical core for large, detailed simulations including Computational Neuroscience and Systems Biology.

MOOSE spans the range from single molecules to subcellular networks, from single cells to neuronal networks, and to still larger systems. It is backwards-compatible with GENESIS, and forward compatible with Python and XML-based model definition standards like SBML and NeuroML.

MOOSE is coordinating with the SMOLDYN project to extend its multi-scale modeling to the level of single-particle reaction-diffusion calculations.

MOOSE is open source software, licensed under the LGPL (Lesser GNU Public License). It has absolutely no warranty.